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Their effectiveness stems from their ability to form disulfide linkages with mucosal surfaces and epithelial TJ proteins

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We hypothesized that these residue differences from IR and IGF1R might be key to the differential recruitment of IRS-1 and Shc, and thereby the activation of different downstream signalling and gene expression pathways

10.1016/j.bbrc.2017.11.159 29 ChenY

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Studies examining full-thickness skin wounds in rats have documented 30-50% increases in wound bed capillary density following GHK-Cu treatment, correlating with 25-40% reductions in time to complete re-epithelialization